Tuesday, September 21, 2021

Study Reveals 'Vaccine Induced Enhanced Disease' May Be Coming Soon


Study Finds The Current Covid-19 Vaccines Will Cause ‘Vaccine Induced Enhanced Disease’ When Infected With Delta


A group of Japanese researchers have released a scientific study showing that the SARS-CoV-2 Delta variant “is poised to acquire complete resistance” to the existing vaccines.

What’s more, when four common mutations were introduced to the Delta variant, Pfizer’s mRNA injection enhanced its infectivity, causing it to become resistant. A Delta variant with three mutations has already allegedly emerged, which suggests it’s only a matter of time before a fourth mutation develops, at which point complete resistance to Pfizer’s jab may be imminent.

The spike protein used in mRNA COVID-19 vaccines consists of the alleged original SARS-CoV-2 spike protein, without mutations. Multiple variants of concern (VOC) have allegedly emerged, however, which have numerous mutations and are highly infectious.

As mutations increase, so do concerns over vaccine resistance and enhanced infectivity. As the researchers explained in bioRxiv, the preprint server for biology:

“The receptor binding domain (RBD) of the spike protein binds to the host cell receptor ACE2, and the interaction mediates membrane fusion during SARS-CoV-2 infection. Neutralizing antibodies against SARS-CoV-2 are mainly directed to the RBD and block the interaction between the RBD and ACE2. Most SARS-CoV-2 variants have acquired mutations in the neutralizing antibody epitopes of the RBD, resulting in escape from neutralizing antibodies.”

When a single mutation was added to the Delta spike, most of the anti-RBD antibodies still recognized it. This wasn’t the case with four mutations, however, which the researchers called Delta 4+. Not only was Delta 4+ not recognised, but infectivity was enhanced:


delta

In short, while Pfizer’s Covid-19 jab still neutralised the Delta variant, when four common mutations were introduced to the RBD, the vaccine lost the ability to neutralize the variant and instead enhanced its infectivity.

“A third round of booster immunization with the SARS-CoV-2 vaccine is currently under consideration,” the researchers explained. “Our data suggest that repeated immunization with the wild-type spike may not be effective in controlling the newly emerging Delta variants.”

Despite the growing recognition that increasing injections may only make matters worse, Israel is currently carrying out a booster shot campaign after recently recording the highest rate of infections over 7 days in the world despite 80% of the population being fully vaccinated. The US and UK have also confirmed they are about to follow suit.






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