"The Omicron spike (S) protein, with an unusually large number of mutations, is considered the major driver of these phenotypes. We generated chimeric recombinant SARS-CoV-2 encoding the S gene of Omicron in the backbone of an ancestral SARS-CoV-2 isolate and compared this virus with the naturally circulating Omicron variant," reads the pre-print.
The authors speculate that their chimeric strain is unlikely to be as deadly in humans as it was in the mice because the specific breed used in testing are more susceptible to severe Covid.
Gain of Function?
"The research is a clear example of gain of function research of concern and enhanced potential pandemic pathogen (ePPP) research," said Dr Richard Ebright, a chemist at Rutgers University in New Brunswick, New Jersey, adding "'It is especially concerning that this new US-government ePPP research - like the previous US-government ePPP research on chimeric SARS-related coronaviruses at Wuhan Institute of Virology that may have caused the pandemic - appears not to have undergone the prior risk-benefit review mandated under US-government policies."
Gain of function research was largely restricted in the US until 2017, when the National Institutes of Health began to allow it to take place using government funds.
Previously it had been halted from 2014 to 2017 over concerns that it could lead to the inadvertent creation of a pandemic. -Daily Mail
Peter Daszak again?
Which leads us to today's report...
Just two months before the '80% mouse kill rate' SARS paper was published, EcoHealth Alliance - the NYC-based nonprofit headed by Peter Daszak (and was also funded by the NIH and Fauci's NIAID to genetically manipulate bat Covid in Wuhan, China) - bragged about a $1 million NSF grant to work with Boston University on a project to 'work towards predicting and preventing future pandemics."
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