The study points out that the number of deaths from any cause among the 1,951,905 children in Sweden (as of December 31, 2019) who were 1 to 16 years of age was 65 during the pre-Covid-19 period of November 2019 through February of 2020 was 65, and 69 during 4 months of exposure to Covid-19 between March and June of 2020.
The data shows that there was no significant difference here.
In a Karolinska Institute press release, lead author and pediatrician Jonas Ludvigsson, MD, PhD, indicated he was hopeful about the results.
“It is very gratifying that serious COVID-19, defined here as needing treatment in an intensive care unit, is so rare among children despite schools being open during the pandemic,” he said.
Jonas F. Ludvigsson, M.D., Ph.D.
Karolinska Institutet, Stockholm, Sweden
jonasludvigsson@yahoo.com
Lars Engerström, M.D., Ph.D.
Vrinnevi Hospital, Norrköping, Sweden
Charlotta Nordenhäll, M.D., Ph.D.
Swedish Association of Pediatric Rheumatology, Stockholm, Sweden
Emma Larsson, M.D., Ph.D.
Karolinska Institutet, Stockholm, Sweden
In mid-March 2020, many countries decided to close schools in an attempt to limit the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus causing coronavirus disease 2019 (Covid-19).1,2 Sweden was one of the few countries that decided to keep preschools (generally caring for children 1 to 6 years of age) and schools (with children 7 to 16 years of age) open. Here, we present data from Sweden on Covid-19 among children 1 to 16 years of age and their teachers. In Sweden, Covid-19 was prevalent in the community during the spring of 2020.3 Social distancing was encouraged in Sweden, but wearing face masks was not.3
Data on severe Covid-19, as defined by intensive care unit (ICU) admission, were prospectively recorded in the nationwide Swedish intensive care registry. We followed all children who were admitted to an ICU between March 1 and June 30, 2020 (school ended around June 10) with laboratory-verified or clinically verified Covid-19, including patients who were admitted for multisystem inflammatory syndrome in children (MIS-C, which is likely to be related to Covid-19)4 according to the Swedish Pediatric Rheumatology Quality Register. (More information on the registry and a link to the Word Health Organization scientific brief on MIS-C are provided in the Supplementary Appendix, available with the full text of this letter at NEJM.org.) The Stockholm Ethics Review Board approved the study. Informed consent was waived by the review board.
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