Thursday, November 3, 2022

Genetic Fingerprint Reveals Synthetic Origin Of SARS-CoV-2

Genetic Fingerprint Reveals Synthetic Origin of SARS-CoV-2


Story at-a-glance

  • According to new research, the chance of SARS-CoV-2 having a natural origin is less than 1 in 100 million. SARS-CoV-2 has a telltale signature of genetic engineering, not previously identified

  • That genetic fingerprint suggests the work of Ralph Baric, Ph.D., was used in the creation of the virus. There’s a direct match between Baric’s published research — which describes how to hide telltale signs of genetic engineering — and the genetics found in SARS-CoV-2

  • In 2002, Baric invented a technique called seamless ligation, which conceals all evidence of genetic engineering in lab-created pathogens. Baric’s nickname for this technique is the “no-see’m method.” Baric taught the method to Shi Zhengli in 2016, and Shi and her colleagues at the Wuhan Institute of Virology (WIV) demonstrated mastery of Baric’s technique in a series of gain-of-function experiments

  • However, while seamless ligation conceals human tampering in lab-created pathogens, the method leaves a signature of its own, and that’s the signature discovered in SARS-CoV-2
  • The findings raise the possibility of liability for the University of North Carolina where Baric works, the National Institutes of Allergy and Infectious Diseases, which funded Baric, the WIV and other parties
According to new research, the chance of SARS-CoV-2 having a natural origin is less than 1 in 100 million.1,2 The paper3 was posted on the preprint server BioRxiv October 20, 2022.


One of its authors, mathematical biologist Alex Washburne, also summarizes the work in a Substack article,4 posted that same day. The other two authors are Valentin Bruttel, a molecular immunologist, and Antonius VanDongen, a pharmacologist. There are two key take-homes from this paper:


  1. SARS-CoV-2 has a telltale signature of genetic engineering, not previously identified
  2. That genetic fingerprint also suggests the work of Ralph Baric, Ph.D., was used in the creation of the virus. There’s a direct match between Baric’s published research — in which he describes how to hide telltale signs of genetic engineering — and the genetics found in SARS-CoV-2
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