What’s more, when four common mutations were introduced to the Delta variant, Pfizer’s mRNA injection enhanced its infectivity, causing it to become resistant. A Delta variant with three mutations has already allegedly emerged, which suggests it’s only a matter of time before a fourth mutation develops, at which point complete resistance to Pfizer’s jab may be imminent.
The spike protein used in mRNA COVID-19 vaccines consists of the alleged original SARS-CoV-2 spike protein, without mutations. Multiple variants of concern (VOC) have allegedly emerged, however, which have numerous mutations and are highly infectious.
“The receptor binding domain (RBD) of the spike protein binds to the host cell receptor ACE2, and the interaction mediates membrane fusion during SARS-CoV-2 infection. Neutralizing antibodies against SARS-CoV-2 are mainly directed to the RBD and block the interaction between the RBD and ACE2. Most SARS-CoV-2 variants have acquired mutations in the neutralizing antibody epitopes of the RBD, resulting in escape from neutralizing antibodies.”
When a single mutation was added to the Delta spike, most of the anti-RBD antibodies still recognized it. This wasn’t the case with four mutations, however, which the researchers called Delta 4+. Not only was Delta 4+ not recognised, but infectivity was enhanced:
In short, while Pfizer’s Covid-19 jab still neutralised the Delta variant, when four common mutations were introduced to the RBD, the vaccine lost the ability to neutralize the variant and instead enhanced its infectivity.
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